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This study shows that the combination of CT imaging and clinical factors pre-neoadjuvant chemotherapy (NAC) for advanced adenocarcinoma of the esophagogastric junction (AEG) could help stratify potential responsiveness to NAC, which can also result in helping to provide a basis for clinicians to develop more customized treatment plans for patients.

Key points

  • Radiomics method can predict that AEG patients can achieve pCR after NAC.
  • The combination of radiomics and clinical factors can improve the predicting performance.
  • Radiomics–clinical model can stratify patients according to potential responsiveness to NAC.
  • Radiomics–clinical model can help clinicians to develop individualized and precise treatment plans.

Article: Enhanced CT-based radiomics predicts pathological complete response after neoadjuvant chemotherapy for advanced adenocarcinoma of the esophagogastric junction: a two-center study

Authors: Wenpeng Huang, Liming Li, Siyun Liu, Yunjin Chen, Chenchen Liu, Yijing Han, Fang Wang, Pengchao Zhan, Huiping Zhao, Jing Li & Jianbo Gao

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